sodium channel blockers การใช้

• All of the peptides are voltage-gated sodium channel blockers.
• Sodium channel blocker lists both extracellular and intracellular classes of these substances.
• It is a sodium channel blocker and therefore classified as a Class 1a anti-arrhythmic agent.
• "' Sparteine "'is a class 1a antiarrhythmic agent; a sodium channel blocker.
• Diphenhydramine also acts as an intracellular sodium channel blocker, which is responsible for its actions as a local anesthetic.
• Sodium channel blockers have been proposed for use in the treatment of cystic fibrosis, but current evidence is mixed.
• Certain anticonvulsant drugs that are classed as Sodium Channel Blockers are now known to make seizures worse in most Dravet patients.
• Imipramine is also known to function as a fast sodium channel blocker, which is said to account for the cardiotoxicity of this agent.
• Most, if not all, of the TCAs also L-type calcium channels, and therefore act as sodium channel blockers and calcium channel blockers, respectively.
• Soon after, the research team identified Wenxin Keli, a herbal Chinese medicine, as an atrial selective sodium channel blocker capable of suppressing atrial fibrillation in experimental models.
• Recently, like its analogue orphenadrine which also has analgesic effects, nefopam has been found to act as a voltage-gated sodium channel blocker, and this may in part or fully mediate its antinociceptive effects.
• Kanki H, Mitamura H, Takatsuki S, Sueyoshi K, Shinagawa K, Sato T, and Ogawa S . Postrepolarization refractoriness as a potential anti-atrial fibrillation mechanism of pilsicainide, a pure sodium channel blocker with slow recovery kinetics.
• These may interfere with electrolyte channels and thus the cardiac action potential ( such as calcium channel blockers, sodium channel blockers ), interfere with stimulation of the heart by the sympathetic nervous system ( beta blockers ), or interfere with the movement of defibrillator may be inserted.
• Over 1280 protein families have been associated with the saliva of blood feeding organisms, including inhibitors of platelet aggregation, ADP, arachidonic acid, thrombin, PAF, anticoagulants, vasodilators, vasoconstrictors, antihistamines, sodium channel blockers, complement inhibitors, pore formers, inhibitors of angiogenesis, anaesthetics, AMPs and microbial pattern recognition molecules, and parasite enhancers / activators.
• "' 4-Iodopropofol "'is a drug derived from the commonly used sedative anaesthetic agent, propofol . 4-Iodopropofol has similar effects to propofol on isolated receptors, acting primarily as a GABA A positive modulator and sodium channel blocker, but when given to animals it has only anxiolytic and anticonvulsant effects, lacking the strong sedative-hypnotic profile of propofol.